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br Conclusions The following are the supplementary
2018-10-23
Conclusions The following are the supplementary data related to this article. Author Contributions Conflict of Interest Acknowledgements This work was supported by the Health Research Institute of University Hospital Clínico San Carlos, “Generalitat Valenciana” (PROMETEOII/2014/065), by
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In addition to the cyclic
2018-10-23
In addition to the cyclic guanosine monophosphate-dependent protein kinase pathway, NO is known to regulate the function of target proteins through S-nitrosylation of cysteine residues (Hess et al., 2005; Jaffrey et al., 2001). One such target is the type 1 ryanodine receptor (RyR1), which is the Ca
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Duchenne Muscular Dystrophy DMD is
2018-10-23
Duchenne Muscular Dystrophy (DMD) is a severe muscle disease affecting 1:3500 male births. DMD is caused by a mutation in dystrophin gene, coding for a protein required for skeletal and cardiac muscle integrity (Mercuri and Muntoni, 2013; Muntoni, 2003; Muntoni et al., 2003). Indeed, dystrophin is a
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A number of lines of evidence
2018-10-23
A number of lines of evidence has suggested BARD1 as a tumor suppressor (Irminger-Finger and Jefford, 2006; Irminger-Finger et al., 2016). BRCA1-BARD1 heterodimer plays a crucial role in homologous repair in response to DNA damage (Stark et al., 2004). The knockout of Bard1 is lethal in mouse (McCar
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farnesyl diphosphate synthase During cell migration GBM cell
2018-10-23
During cell migration, GBM cells require modifying their cellular volume to go through narrow spaces; these changes in volume are regulated through ionic transport (Watkins and Sontheimer, 2011). Ion co-transporters, such as the Sodium Potassium Chloride co-transporter (NKCC1) 1, regulate intracellu
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br Search Strategy and Selection Criteria Data
2018-10-23
Search Strategy and Selection Criteria Data for this review were identified through PubMed and references from relevant articles using the search terms “interferon signature”, “type 1 interferon signature”, “type 1 diabetes”, “Coxsackieviruses”, “type 1 interferonopathy”, “autoimmune diseases”. A
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br Data After growing Salmonella Typhimurium bacteria under
2018-10-23
1. Data After growing Salmonella Typhimurium bacteria under a variety of environmental conditions, bacterial survival was determined after exposure to oxidative stress. Secondly, the production of endogenous hydrogen peroxide was measured of bacteria that were grown to different growth phases. La
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Kinematic data were low pass filtered
2018-10-23
Kinematic data were low-pass filtered (15Hz cutoff; Matlab R2012a), ground reaction force data were low-pass filtered (50Hz cutoff), and internal joint moments were computed using matched filter cutoffs (15Hz). EMG data were band pass filtered (15–300Hz cutoff), full-wave rectified, and low-pass fil
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The analysis with the Autodyn
2018-10-22
The analysis with the Autodyn program included calculations (“runs”) with the Johnson–Cook and von Mises strength models focused on showing agreement with the Hohler–Stilp data for L/D = 10 tungsten penetrators impacting thick HzB,A steel targets (see the Appendix). The analysis included a study of
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Este n mero abre con los hasta
2018-10-22
Este número abre con los “hasta prontos”. Marta Lamas, Hortensia Moreno, Jean Franco y Dora Cardaci han escrito cada una LY 2157299 su manera su texto de una despedida que no lo es (dice Lamas). O que sí (llora Jean Franco). Un hasta luego, dice Cardaci. Un pretexto para hacer balance (Moreno). Cada
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Seg n el Informe Anual de la ILGA durante su
2018-10-22
Según el Informe Anual de la ILGA (1989), durante su Decimoprimera Conferencia Anual en Viena, y con el apoyo de activistas de organizaciones de México, los afiliados austriacos de GOHL propusieron que la Decimotercera Conferencia Anual tuviera lugar en Guadalajara, México. Los participantes de la c
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br Acknowledgement br Introduction The reason why leadership
2018-10-22
Acknowledgement Introduction The reason why leadership maters a lot in organizational behavior studies is evident from the fact that, since 2000, organizations have spent $50 billion per year on the leadership development (McCallum & Connell, 2009). Recent studies also indicated an increase in
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br Conclusion br Acknowledgements We would like to
2018-10-22
Conclusion Acknowledgements We would like to thanks the editors and the anonymous referees of the journal for constructive comments and suggestions, which have significantly helped to improve the contents of the paper. Furthermore, special thanks to Fundamental Research Grant Scheme (FRGS) Vot
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br Biochip Microarray provides rapid accurate high throughpu
2018-10-22
Biochip/Microarray provides rapid, accurate, high throughput measurements for proteins and nucleic acids, which is a promising technology in many biomedical fields Biochips are essentially miniaturized laboratories. Microarray is the critical component of a biochip platform. Microarrays consists
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br On history What is the history
2018-10-22
On history What is the history of architecture for Banham? History as a system of knowledge is undoubtedly important for Banham because of its resourceful nature for future improvement and correction. Even though historical accounts on Banham\'s works have been the main concern of Whiteley\'s boo
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