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Importa recordar que el intelectual acad mico siempre se
2019-06-12
Importa recordar que el intelectual académico siempre se ha sentido incómodo en su propia piel. Leer y escribir rigurosamente pueden ser actos radicales en sí, pero la relación del intelectual y la academia suele exigir sospecha, mucho más que la del artista y el mercado, o la del político y el part
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Polymorphic VT VF storms can occur
2019-06-11
Polymorphic VT/VF storms can occur in patients with severe Cilengitide failure, independent of their underlying causes. Recent experimental studies using a pacing-induced heart failure model showed that heart failure facilitates acute shortening of the APD immediately after VF termination [73]. Per
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MIP binds to three different receptors CCR
2019-06-11
MIP-1α binds to three different receptors: CCR1, CCR5 and CCR9. CCR1 and CCR5 are expressed on MM calcifediol and stromal cells. Inhibitors to CCR1 and CCR5 have been used to delineate the roles of each receptor in the myeloma bone marrow microenvironment[69]. Menu and colleagues demonstrated that
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MiR a rs is situated in
2019-06-11
MiR-196a2 rs11614913 is situated in the 3′ passenger strand mature sequence of miR-196a2. The C to T mutation of the rs11614913 SNP, which was located in the stem region of an miR-196a-2 precursor, leads to a change from a G:C to a G:U mismatch. A previous study has shown that miR-196a2 rs11614913 c
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According to several cases earlier reported by Gandhi
2019-06-11
According to several cases earlier reported by Gandhi et al, the median time of acute pancreatitis occurring is 12 days (range: 9–16 days), from the last administration of BV, and most events occurred in the first course of BV treatment. One patient experienced recurrent pancreatitis in the fifth co
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In addition to inducing IKs dysfunction through dominant
2019-06-11
In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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The participants discussed several overarching themes conclu
2019-06-11
The participants discussed several overarching themes, concluding that research is too often separate from implementation. A crucial gap remains between the development of efficacious health interventions and their optimum delivery in real-life settings. This gap is particularly true in many low-inc
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Ya en el siglo xx
2019-06-11
Ya en el siglo xx, la Historia verdadera (y las crónicas de Indias en general) ha sido recuperada como origen de la literatura latinoamericana contemporánea, en especial por escritores vinculados sodium channel blockers la literatura del boom: Alejo Carpentier, Gabriel García Márquez, Carlos Fuentes
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br A modo de conclusi
2019-06-11
A modo de conclusión La re/visión que se ha propuesto en el presente escrito recoge el sentido que le da Adrienne Rich al término: revisar es volver a mirar desde un posicionamiento crítico en un presente, desde el que se tiene una perspectiva (temporal) de cómo ha sido la suerte del fenómeno que
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Conflict of interest br Authors contributions br Acknowledgm
2019-06-11
Conflict of interest Authors׳ contributions Acknowledgments This work was supported by grants from the Associazione Italiana Lotta alle Leucemie, Linfoma e Mieloma (AIL) – Sezione ‘Luciano Pavarotti’ Modena-ONLUS (to FF and LP) and from the Associazione Italiana per la Ricerca sul Cancro (AIR
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br Over the past decade a
2019-06-11
Over the past decade, a growing number of studies have linked urban green space and aspects of citco with emotional wellbeing. Although the existing body of epidemiological work has been very encouraging—collectively providing a strong argument that access to areas rich in vegetation, bodies of w
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First Speakman and colleagues do not mention the development
2019-06-11
First, Speakman and colleagues do not mention the developments in the 2000s, when notable EU attention was given to global health. In 2010, there was a high-level conference and the launch of a European Commission Communication, which stated that the EU\'s commitment to global health should mainly f
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The primary tool in the pharmacological
2019-06-11
The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress
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br Conclusion br Introduction Multiple myeloma is a malignan
2019-06-10
Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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simvastin br Methods br Results Globally
2019-06-10
Methods Results Globally, CCI increased by 0·82 percent points a year, from 54·8% in 1994, to 71·2% in 2014 (CCI estimates at national level, stratified by wealth quintiles and place of residence, are presented in the appendix, pp 6–15). This gain was largely driven by low-income countries, wh
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