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br Methods br Discussion We observed a
2019-05-29
Methods Discussion We observed a significantly lower than expected Day +100 TRM. Other NMAT studies [4,5] have shown similar findings, although 60% of our trial thiostrepton had high risk disease per the CIBMTR classification. In this and other studies, late TRM and disease progression remain
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The imbalances in the current R D system were the
2019-05-29
The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle
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buprenorphine hydrochloride Importance of heart failure Acut
2019-05-29
Importance of buprenorphine hydrochloride failure Acute decompensated heart failure (ADHF) refers to a clinical condition of worsening HF with dyspnea, often with evidence of fluid overload [1]. This is generally triggered by 1 of the 4 main factors: atrial fibrillation, anemia, hypertension, and
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br Panels A to D
2019-05-29
Panels A to D show intracardiac recordings of the HRA extrastimuli with A1A2 intervals of 320−290ms at a basic CL of 600ms. The AV conduction intervals were increased gradually rather than suddenly, so that an Ae with an A2–V2–Ae sequence could be provoked only at 310ms and 300ms, followed by no A
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Introduction Several types of cancers
2019-05-29
Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s
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The presence of an inflammatory infiltrate is associated wit
2019-05-29
The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha
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After being secreted into bile and
2019-05-29
After being secreted into bile and entering the intestine, ∼95% of the bile acids are returned to the liver through the enterohepatic circulation via an active transport and order Tenovin-6 by a specific bile acid transporter, apical sodium-dependent bile acid transporter predominantly in the dista
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As found in the previous study miR was
2019-05-28
As found in the previous study, miR-101 was significantly downregulated in CCA tumors compared with adjacent non-tumor tissues and this was supported by work from another group. This publication also found that miR-101 hepatic levels were decreased in CCA tumors compared with adjacent non-tumor tiss
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nicotinic receptor agonist Tambi n debemos tener presente el
2019-05-28
También debemos tener presente el horizonte en el que se inscriben colecciones como la aquí revisada. Si aceptamos que nos encontramos bajo un panorama de fragmentación del conocimiento y segmentación de las disciplinas, se muestra fundamental la recuperación de la toma de partida por la cultura, en
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Ad Mapu lleg a convertirse en un
2019-05-28
Ad Mapu llegó wee1 convertirse en un gran referente que contribuyó al fortalecimiento de la conciencia de la situación mapuche, así lo explica Víctor Toledo al mencionar que es en este momento cuando aparece bosquejada la autodeterminación como propuesta del pueblo mapuche, y recuerda las palabras d
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En Am rica Latina los a os noventa constituyen la
2019-05-28
En América Latina, los años noventa constituyen la década en la que los reclamos en términos de políticas de identidad en torno iib iiia inhibitors la raza y la etnicidad, que habían comenzado en la década anterior, adquirieron su mayor densidad acompañados por las reformas constitucionales que conv
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Es por supuesto en La raz
2019-05-28
Es, por supuesto, en La razón populista y en textos sucesivos donde se desarrolla la teoría política del populismo en toda su complejidad Mifepristone partir de una serie de rupturas que constituyeron el posmarxismo de Laclau. Como el propio autor insinuaba en la obra de 1987, en esta teoría del pop
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Common and rare SCN A variants may
2019-05-28
Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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Besides MPO the infiltrated neutrophils in IR injured liver
2019-05-27
Besides MPO, the infiltrated neutrophils in IR injured liver can produce INFγ to enhance TLR4 signaling, stimulate KCs activation, and induce Th1 inflammation responses. Subsequently, M1/Th1 CX-4945 Supplier produce INFγ to enhance neutrophil infiltration in the process of hepatic and renal IR injur
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br Discussion Early repolarization is a common ECG
2019-05-27
Discussion Early repolarization is a common ECG characteristic. Its reported prevalence is 6–25% of the general population, and is particularly common in athletes [2,3,11,12]. It is now recognized that a small fraction of people with early repolarization on their ECGs develop lethal tachyarrhythm
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