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In the current study we showed that known
2024-10-23
In the current study, we showed that known inhibitors of the F-ATPase and ionophores affect the growth of P. gingivalis and its plasma membrane ATPase, suggesting that the membrane ATPase can be a target for anti-periodontitis agents. We also identified stilbenoids that strongly inhibit the growth o
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It was reported that overexpression
2024-10-23
It was reported that overexpression of the rat ACL gene in tobacco increased the total ACL activity by 4 fold, which increased the production of fatty acids by 16% [8]. Recently, a 1.7-fold increase of fatty acids and 1.9-fold increase of triacylglycerol (TAG) was observed in Aspergillus oryzae with
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fak pathway The elevated levels of intracellular antioxidant
2024-10-22
The elevated levels of intracellular antioxidant such as reduced glutathione (GSH) are normally oberserved is various tumor fak pathway which confers the chemoresistant to chemotherapy [59]. Therefore, the induction of oxidative stress via elevation of intracellular ROS and dimunition of intracellu
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Introduction Enzymatic browning degrades quality
2024-10-22
Introduction Enzymatic browning degrades quality, safety, and nutritional values of various fruits or vegetable products. For example, the color of apple or potato is generally yellowish, representing freshness. However, they are extremely susceptible to enzymatic browning because of abundant polyp
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We also explored the possibility that
2024-10-22
We also explored the possibility that this PKC-θ activating protein could operate on the auto-phosphorylation process of the kinase, a specific event accompanying PKC activation [32]. The heated PKC-θ immunoprecipitate from metaphasic cells was then added to PKC-θ isolated both from interphasic or m
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Consistent with the above prediction there are
2024-10-22
Consistent with the above prediction, there are additional reports in which HMGA proteins have been demonstrated to facilitate recruitment of chromatin remodeling complexes to gene regulatory regions containing positioned nucleosomes during the transcriptional activation process. One particularly il
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br Results br Discussion Although the value
2024-10-22
Results Discussion Although the value of ID specialists in the USA has already been described in the literature, this study suggests that the same holds true for the Japanese healthcare environment [7], [17], [18], [19]. Valerio et al. reported that antifungal use in DDD decreased from 66.4 pe
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Moreover a multiple regression analysis using the year
2024-10-22
Moreover, a multiple regression analysis using the 1-year MMSE score as a dependent variable was conducted. The result showed that serum Phorbol 12,13-dibutyrate mg levels at admission did not affect the MMSE score 1 year later (β = 0.10, p = 0.639). Discussion In this study, serum Aβ42 levels
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br Materials and methods br Conflict
2024-10-22
Materials and methods Conflict of interest Acknowledgments We thank Christine Heiner (Department of Surgery, University of Pittsburgh) for her critical reading of the manuscript. This work was supported by grants from the US National Institutes of Health (R01GM115366, R01CA160417, and R01CA
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Scutellaria moniliorrhiza Komarov Labiatae is a perennial
2024-10-22
Scutellaria moniliorrhiza Komarov (Labiatae) is a perennial herb and mainly distributed in Jilin province, China. In traditional Chinese medicine, the whole plants have been used to clear away heat-evil, expel superficial evils, eliminate stasis and reduce edema (He et al., 2012). In previous phytoc
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Based on our previous work and the observation that
2024-10-22
Based on our previous work [13] and the observation that SNX9 is a partner for ACK, we have investigated interactions involving the SH3 domain of SNX9, and identified for the first time synaptojanin-1 as an alternate partner. This SH3 domain can bind a single site in ACK1, but multiple sites in the
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br Results br Discussion Our finding that AXL overexpression
2024-10-21
Results Discussion Our finding that AXL overexpression is significantly associated with poor survival in patients with high-grade serous OC is consistent with previous reports indicating that AXL regulates tumor growth in some cancers, as well as reports showing that AXL activity is involved i
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The physiologic conditions and signaling
2024-10-21
The physiologic conditions and signaling mechanisms that regulate apelin secretion and APLNR expression in malignant tissues appear to be multifactorial. Previous studies have shown that hyperplastic and neoplastic cholangiocytes secrete a variety of hormones, peptides, and growth factors that help
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Introduction According to Uganda s Ministry of Health
2024-10-21
Introduction According to Uganda's Ministry of Health (MOH 2012a:91), intermittent preventive treatment (IPT) to avoid malaria during pregnancy is a free preventive service available to all pregnant women without clinical signs and symptoms of malaria, attending prenatal clinics. However, pregnant
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br Conclusions and perspectives In view of the evidences
2024-10-21
Conclusions and perspectives In view of the evidences supporting that Alarelin Acetate MAS receptors mediate the effects of AT1 antagonists (Iwai et al., 2012, Ohshima et al., 2014, Pernomian et al., 2015, Schuchard et al., 2015), the prime targets from the perspectives on future directions in t
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