• br Genes involved in oxysterol metabolism The

  2020-10-13

  

  Genes involved in oxysterol metabolism The main enzymes that participate in the metabolism of oxysterols generally belong into one of two groups: transferases or oxidoreductases [22]. The following chapter describes those genes of oxysterol metabolism whose polymorphisms have been associated with

• br Conformational Activation of APC C Enables Binding to

  2020-10-13

  

  Conformational Activation of APC/C Enables Binding to the Coactivator CDC20 APC/C comes to life by binding a coactivator. This is controlled in part by phosphorylation and APC/C conformational changes that expose the NVP-BSK805 receptor for the C box and IR tail of the coactivator. In interphase

• Picrotoxin br DUBs in regulation of critical steps in

  2020-10-13

  

  DUBs in regulation of critical steps in tumor metastasis Tumor metastasis comprises a complicated series of biological processes in terms of the invasion-metastasis cascade that requires cancer Picrotoxin to (1) migrate and invade from the origin sites through the extracellular matrix (ECM) to t

• Previous studies have indicated that hSSB may be

  2020-10-13

  

  Previous studies have indicated that hSSB1 may be phosphorylated at threonine residue 117 (T117) [13] and acetylated at lysine residue 94 (K94) [15], both of which promote hSSB1 function in response to ionising radiation exposure. Mass spectrometry screens of proteins immunoprecipitated with phospho

• It is well known that nanostructured

  2020-10-13

  

  It is well known that, nanostructured transition metal oxides are the most promising candidates as electrode for pseudocapacitors due to their attractive properties such as environmentally friendly, high theoretical capacitance, low cost and easily abundant [15], [16]. Numerous investigations have b

• DGK is also involved in cell differentiation Previously to

  2020-10-13

  

  DGKδ is also involved in cell differentiation. Previously, to investigate the physiological roles of DGKδ, DGKδ-deficient mice have been generated. On the basis of the analysis of DGKδ-deficient mice, Crotty et al. reported that DGKδ regulates the epidermal growth factor receptor (EGFR) pathway by a

• br Materials and methods br Results

  2020-10-13

  

  Materials and methods Results Discussion The present work demonstrates the functional role of DGAT2 in elevating the neutral lipid accumulation in engineered N. oceanica, which have aroused a great deal of interest in industrial scale biofuel production. Recently, there have been increasing

• Studies of Jelski and Szmitkowski show that

  2020-10-13

  

  Studies of Jelski and Szmitkowski show that differences of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activity between o-Phenanthroline of many cancers and healthy tissue may be one of the factors intensifying carcinogenesis [7]. Moreover, changes of ADH and ALDH activity in canc

• Cryptosporidium is a protist causing serious diarrhea in hum

  2020-10-13

  

  Cryptosporidium is a protist causing serious diarrhea in humans and other animals (Bouzid et al. 2013). In its mitosomes, the most reduced forms of mitochondria, it is assumed that the membrane potential is generated by a simple respiratory chain consisting of transhydrogenase, type II NADH dehydrog

• Collagen compaction and alignment are generated by cell medi

  2020-10-13

  

  Collagen compaction and alignment are generated by cell-mediated contractile forces (Stopak and Harris, 1982). The transmission of actomyosin forces to collagen has been mainly attributed to integrins and the activation of the Rho-ROCK pathway (Clark et al., 2007, Kural and Billiar, 2013, Provenzano

• The excitatory amino acid L glutamate or glutamate

  2020-10-13

  

  The excitatory amino gip receptor L-glutamate or glutamate mediates most of the excitatory neurotransmission within the mammalian central nervous system (CNS) and has been implicated in numerous peripheral nervous system (PNS) pathways. The excitatory amino acids, including glutamate, are of great

• As mentioned previously dopamine plays

  2020-10-12

  

  As mentioned previously, dopamine plays a crucial role in reducing prefrontal cortical suppression to the amygdala (Rosenkranz and Grace, 2001) and prefrontal cortex mediated amygdala supression has recently been associated with vagal regulation of HRV (Sakaki et al., 2016). In addition, evidence ha

• Among the members of the GH

  2020-10-12

  

  Among the members of the GH106 family, which groups 319 different sequences, a single 3D-structure has been reported, the BT0986 from Bacteroides thetaiotaomicron that shows a (β/α)8 barrel and catalyzes the hydrolysis of an α-l-rhamnopyranoside bound to the C2 position of an arabinofuranoside (L-Rh

• Both progesterone and the calcium ionophore

  2020-10-12

  

  Both progesterone and the calcium ionophore A23187 rely on the synthesis of cAMP by sAC to elicit exocytosis in human sperm (Fig. 2E-H and [8], [60]). We had reported earlier that digestion of endogenous cAMP with recombinant cAMP-specific phosphodiesterase 4D [9] or inhibition of its synthesis with

• br Activatable bioorthogonal reactions reagents

  2020-10-12

  

  Activatable bioorthogonal reactions/reagents Cyclopropenes as bioorthogonal reagents for IEDDA substrates Cyclopropenes have become popular bioorthogonal reagents due to their small size, inertness to biological nucleophiles, ability to be genetically encoded (Yu et al., 2012), and participati

15125 records 704/1009 page Previous Next First page 上5页 701702703704705 下5页 Last page