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At baseline mutant allele frequency of
2019-07-02
At baseline, mutant allele frequency of EGFR in tissue and plasma samples did not correlated with anti-tumor response (Supplementary Fig. 1). Among 35 patients who were positive for cell-free DNA (cfDNA) at baseline, changes of cfDNA during treatment were analyzed. Negative conversion (NC) of cfDNA
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Results from H also complement work of the AICPA
2019-07-02
Results from H5 also complement work of the AICPA Board of Examiners, which has concluded “newly licensed CPAs must demonstrate higher-order skills such as critical thinking, problem solving, analytical ability, and skepticism more frequently. It is critically important that newly licensed CPAs are
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Our published results also show that the Y
2019-07-02
Our published results also show that the Y2 and the Y5, but not the Y1, receptors mediate NPY-induced excitation-secretion coupling in EECs (Abdel-Samad et al., 2012). Thus, it is highly important to consider controlling ET-1 circulating level via blockade of Y2 and/or Y5 receptor activation (Abdel-
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Current therapeutic protocols in OS and ES consist
2019-07-02
Current therapeutic protocols in OS and ES consist of neoadjuvant chemotherapy and local surgical resection, followed by adjuvant chemotherapy. These treatments lead to a 70% overall survival for localized disease but can decrease to 15% in case of metastasis. With CS being resistant to conventional
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The most common pathology associated with FGR is poor
2019-07-02
The most common pathology associated with FGR is poor placental perfusion as a result of abnormal placentation [4]. Placental developmental disorders and insufficient hormone synthesis may lead to FGR [5,6]. However, the exact mechanism responsible for abnormal placental development remains unclear
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Fermentation process for growth of E coli BL DE
2019-07-01
Fermentation process for growth of E. coli BL2(DE3)/pBMS–P3Hcys was carried out in 25- and 380-L fermentors containing 15- and 250-L medium, respectively. Cell yield of about 100g/L (wet cells) was achieved by feeding glycerol and Hy-yest during fermentation. Typical fermentation parameters are show
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Material and Methods We reviewed the following
2019-07-01
Material and Methods We reviewed the following databases to obtain relevant studies of udenafil: PubMed, Embase, and the Cochrane Library. The following search terms were used: (“udenafil” OR “Zydena” OR “DA 8159”) AND (“Erectile Dysfunction” OR “Impotence”). We also searched the references of incl
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For many years international donors philanthropists and char
2019-07-01
For many years, international donors, philanthropists, and charities have poured money into deworming programmes for children in low-income and middle-income countries in the belief they will contribute to improved health, school performance, and economic development. The Rockefeller Sanitary Commi
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br Methods br Results In
2019-07-01
Methods Results In 22 patients, we analyzed 82 sites at which HFS was delivered. We identified 57 GP-positive sites on the basis of a vagal response (19 at the MTGP, 18 at the SLGP, and 20 at the ARGP) and 25 GP-negative sites. After delivery of radiofrequency STF-62247 (30–35W for 30s) to t
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Introduction In current rehabilitation practice for
2019-07-01
Introduction In current rehabilitation practice for most clinicians, restorative, supportive and palliative rehabilitation are the primarily courses of treatment for colorectal cancer (CRC) patients in Taiwan. When the end result of treatment for any patient is a fully functional recovery, restorat
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Myriocin br Conflict of interest br Authors contributions br
2019-07-01
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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There are few learning points that can
2019-07-01
There are few learning points that can be derived from this case. While VDD is an acceptable mode in young patients, one should be cautious of using this mode in elderly patients with sick sinus syndrome, unless retrograde VA conduction is absent. A single PVC can trigger a ventricular paced rhythm
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The TP related complications are given in
2019-07-01
The TP-related complications are given in Table 3. Pericardial effusion without tamponade was seen in 2 patients (5.9%) in the TEE-guided TP group and 5 (8.8%) in the fluoroscopy-guided group. There was no pericardial tamponade in the TEE-guided group and only one patient experienced tamponade in th
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La representaci n colectiva de
2019-07-01
La representación colectiva de los indígenas se caracteriza por el tono apologético, idealizado, en el que el uso abundante de los superlativos contribuye Coumarin resaltar hiperbólicamente la naturaleza pacífica del nativo como “buen salvaje”: Siguiendo el esquema de las oposiciones binarias, Las
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br Hacia un monote smo ta no Debido
2019-07-01
Hacia un monoteísmo taíno Debido al hecho de que la irreductible diversidad de los cemíes parece demasiado peligrosa para ser comparada con la noción antigua de divinidad, la Relación trata de proponer, aunque de manera discreta, otra forma de interpretación: es decir, la búsqueda de las huellas
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