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In the present study we firstly confirmed the resistance
2019-05-17
In the present study, we firstly confirmed the resistance of osteosarcoma U2OS cannabinoid receptor to doxorubicin under hypoxia via inhibiting the drug-induced apoptosis. The hypoxia pre-treatment could significantly ameliorate the viability reduction in U2-os cells which were treated with doxorub
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The congruence between BrS and
2019-05-17
The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope
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Currently we are unable to fully understand the
2019-05-16
Currently, we are unable to fully understand the pak1 and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the present cas
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The most compelling apparent evidence
2019-05-16
The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B
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Is this perhaps a manifestation of the unequal distribution
2019-05-16
Is this perhaps a manifestation of the unequal distribution of growth, reflecting a pattern whereby income increases over the past two decades have benefited only the better-off? The evidence suggests that this is unlikely: across countries, Vollmer and colleagues report similar associations between
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In the largest published case series Rossi
2019-05-15
In the largest published case series, Rossi et al. identified seven cases of infant B-ALL, including three cases of congenital leukemia, with lineage switch from B-lymphoid to myelomonocytic leukemia [12]. An additional two cases were described with a switch from AML M5 to B-ALL. Of the nine describ
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It is noteworthy that in a recent study Le Scouarnec
2019-05-15
It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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The participants discussed several overarching themes conclu
2019-05-15
The participants discussed several overarching themes, concluding that research is too often separate from implementation. A crucial gap remains between the development of efficacious health interventions and their optimum delivery in real-life settings. This gap is particularly true in many low-inc
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Angler a registra la fauna en
2019-05-15
Anglería registra la ptio manufacturer en forma dispersa y fragmentaria; sucede casi siempre como una anécdota curiosa de marcado carácter digresivo o cuando el espécimen difiere ostensiblemente de los conocidos o es portador de alguna maravilla; además en su recepción y representación hay resabios
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cam kinase ii br Discussion Appendicitis is seen in the gene
2019-05-15
Discussion Appendicitis is seen in the general population with a lifetime cumulative incidence rate of 9% [7]. Our calculated incidence rate of appendicitis in the setting of acute leukemia (1.9%) correlates with the reported incidence of 0.5–4.4% [1]. Leukemic involvement of the gastrointestinal
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However Ethiopia is addressing this situation
2019-05-15
However, Ethiopia is addressing this situation head-on. To increase access to oxygen and pulse oximetry, the Ethiopian Ministry of Health (MOH) has responded by undertaking a comprehensive strategic planning process captured as a roadmap for oxygen and pulse oximetry scale-up. A national technical w
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With respect to the ST elevation in the
2019-05-15
With respect to the ST elevation in the precordial lead, Antzelevitch et al. demonstrated that this can be an cftr of early repolarization or J-wave caused by transient outward current (Ito)-mediated transmural differences in the early phases of the action potential. BS is an inherited disease with
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During a mean of months
2019-05-15
During a mean of 41±29 months of follow-up, freedom from VT or VF was observed more frequently in the non-inducible group (24 of 30 (75%)) than in the inducible group (9 of 21 (43%), P=0.03). The estimated cumulative freedom from VT or VF was 88%, 83%, 75%, and 55% at the 1-, 2-, 3-, and 5-year foll
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En las lecturas contextualizadas por el entorno pol tico el
2019-05-15
En las lecturas contextualizadas por el entorno político el lado “afrancesado” de MGN es justificado. Para Carlos Monsiváis no solamente era el autor sino la ciudad que exaltaba su posibilidad de llegar amc 7 parecerse a París (2006: 39). Se presenta un cosmopolitismo y afrance-samiento que halaga a
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Although second malignancies are increasingly observed after
2019-05-14
Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo
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