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Heat shock facilitates the folding of various
2019-06-27
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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Nafamostat Mesylate This Ca overload activates the forward m
2019-06-27
This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ
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br Although much attention centres on Afghanistan s
2019-06-27
Although much attention centres on Afghanistan\'s political and security transitions, malnutrition is a foremost concern. Because an absence of adequate nutrition has crucial long-term effects on individuals and on social and economic development, nutrition rates in Afghanistan deserve attention a
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br Conformational control inhibition Conformational escape r
2019-06-27
Conformational control inhibition Conformational escape resistance is a phenomenon where point mutations (such as T315I) drive the Abl kinase toward the active type I state. “Switch-control inhibitors” bind in a non-ATP-competitive fashion to residues (E282, R386) the Abl protein uses to switch b
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We did a qualitative analysis to estimate the potential risk
2019-06-27
We did a qualitative analysis to estimate the potential risk of Zika Captopril introduction into the country. We used the circlize statistical package for R software to visualise incoming traffic (logarithm of relative passenger volume) to Pakistani airports from countries characterised as Zika-viru
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El presente art culo busca exponer
2019-06-26
El presente artículo busca exponer un panorama general de la dinámica de movilización y representación política emprendida por los principales movimientos sociales presentes en Perú, los cuales se desenvuelven en un contexto signado aún por las reformas estructurales, los cambios constitucionales y
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Un segundo aspecto que deber a ser considerado
2019-06-26
Un segundo aspecto que debería ser considerado para entender cabalmente por qué estas parentelas nobiliarias indígenas de Xolloco Acatla mostrarían una notable reluctancia PQ 401 relacionarse con los poderes de San Pablo, y, por el contrario, habrían exhibido una interesada vinculación con los de Sa
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The diagnosis of PTC based on the Modified Dandy Criteria
2019-06-26
The diagnosis of PTC, based on the Modified Dandy Criteria, is made when a patient exhibits an elevated LP opening pressure above 25cm H20 with normal CSF composition and radiologic findings, and no other explanation for the rise in intracranial pressure [6]. The most common presenting symptom occur
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Interpretation In Haiti the creation
2019-06-26
Interpretation In Haiti, the creation of a national-level, centralised registry has facilitated the diagnosis of patients with surgical heart disease; accelerated the expansion of surgical options for these patients; and has helped to catalyse the development of permanent surgical capacity in Haiti
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Both stunting and environmental enteric dysfunction improve
2019-06-26
Both stunting and environmental enteric dysfunction improve with radical shifts in environment, such as NU 9056 structure or local economic development. This improvement is reflected to some extent by the smoothing of the seasonality of undernutrition reported by Nabwera and colleagues in these thr
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In general we measured the skin temperatures
2019-06-26
In general, we measured the Meropenem temperatures of 135 acupoints in healthy students. The skin temperatures of these acupoints had consistency at a narrow range of 34.88–36.14°C, but had differences among them arising in part from concentricity distribution to keep whole body warmness. Skin acup
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br Signal averaged electrocardiography SAECG
2019-06-26
Signal-averaged electrocardiography (SAECG) SAECG is a high-resolution electrocardiographic technique developed in the 1970s for detecting patients who are prone to SCD after MI. It is based on the theory that lethal ventricular arrhythmias leading to SCD often have a reentrant mechanism. Reentry
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Brugada syndrome BS is a hereditary arrhythmogenic disease
2019-06-26
Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada f
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br Discussion The differential diagnosis
2019-06-26
Discussion The differential diagnosis of ATA with a constant CS activation sequence following PV isolation for AF includes (a) AF originating from a non-PV focus [1], (b) focal ATA, and (c) macro-reentrant AFL of LA or RA origin [2–4]. First, the proximal-to-distal CS activation sequence during t
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br Las paradojas de un escritor norteamericano S
2019-06-26
Las paradojas de un escritor norteamericano Séptima novela de Hergesheimer, Tampico está considerada entre las menos artísticas que escribió. Tal vez el choque con la descarnada realidad del enclave petrolero Tirofiban hydrochloride monohydrate puso en cuestión, hasta cierto punto, su vocación es
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