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br Materials and method br Results br Discussion The
2018-11-07
Materials and method Results Discussion The present study was one of the first to examine the predictive effect of executive functioning on the initiating of the first alcoholic drink and binge drinking episode among young adolescents, and the first to examine adolescents who were alcohol-n
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egfr pathway Methodological differences across studies can c
2018-11-07
Methodological differences across studies can contribute to explain these different patterns of results. Neuroimaging studies on adults highlight the strong impact of literacy on spoken word responses when people perform explicit tasks (e.g., rhyming, repetition, lexical decision tasks; Castro-Calda
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Among potential health beneficial effects in vitro assessmen
2018-11-06
Among potential health beneficial effects, in vitro assessment of fermented foods isolates for their hypocholesterolemic effect has been done by some researchers [16,31,45]. Cholesterol binding by LAB in the small intestine may reduce the amount of dietary cholesterol absorbed [31]. Several mechanis
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br Acknowledgments br Introduction Mouse embryonic stem ES c
2018-11-06
Acknowledgments Introduction Mouse embryonic stem (ES) ppar pathway can give rise to all somatic cell types and germ cells in a regulative manner and are thereby defined as pluripotent. They are thought to have ‘no pre-determined programme’. However, whether or not an ES cell represents a ‘ta
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br Introduction Stem cell divisions resulting
2018-11-06
Introduction Stem cell divisions resulting in alternative pathways of self-renewal or differentiation require very distinctive epigenetic regulation of gene expression from the same genome. Where division has a symmetrical output of progeny cells, the assumption is that the molecular signatures d
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br Introduction Transplantation of hepatocytes
2018-11-06
Introduction Transplantation of hepatocytes (HTx) has been shown to be useful for patients with chronic or acute liver failure or genetic defects in liver function (Strom et al., 1997; Fisher et al., 2000; Fisher and Strom, 2006; Strom et al., 2006; Fox et al., 1998; Horslen et al., 2003; Muraca
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tsa trichostatin We hypothesized that type B astrocytes migh
2018-11-06
We hypothesized that type B astrocytes might be among the other SVZ-derived cell types able to migrate in response to a damage insult. In this study we used Nilo1, a previously characterized mAb that identifies early neural progenitors in the SVZ niche (Del Valle et al., 2010), demonstrating that Ni
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To ultimately test the functional pacemaker activity of the
2018-11-06
To ultimately test the functional GSK343 activity of the iSABs, we took advantage of the ex vivo model based on cultivated ventricular slices of murine hearts (Halbach et al., 2006; Figure 6A). Although such slices typically have spontaneous beating activity immediately after preparation, they can
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Although due to limitations of
2018-11-05
Although, due to limitations of the current tools and technical challenges, we could not perform direct manipulation of the 11 miRNAs to rescue/inhibit neurogenesis in vivo, we demonstrated that most of these miRNAs are expressed in adult-born hippocampal neurons, and consequently depleted upon the
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The molecular mechanisms underlying calreticulin s effects
2018-11-05
The molecular mechanisms underlying calreticulin\'s effects on cardiac development continue to be elucidated. It is known that intranuclear translocation of cardiogenic transcription factors is affected by calcineurin, a Ca2+∕calmodulin-regulated cytosolic phosphatase (Crabtree, 1999; Frey et al., 2
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The value of can be significantly lower than
2018-11-05
The value of can be significantly lower than the initial elastic modulus of the material containing no hydrogen, as The above equation clearly illustrates the strong effect that the concentration of the attached hydrogen particles has on the total elastic modulus: the higher the proportion of the
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Expansion is a canonical white noise expansion in terms
2018-11-05
Expansion is a canonical white-noise expansion in terms of a wavelet basis, i.e., it is a sum of random quantities multiplied by determinate time-varying functions, in this case, wavelet ones. Amiantov\'s study proved, in particular, the assumption that the probability density functional takes the
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In agreement with the results of
2018-11-05
In agreement with the results of the previous studies conducted in our laboratory, it was found that the regulation of the STIM2→nSOCE signaling pathway was impaired in 5×FAD mice. It was established that downregulated STIM2 expression was observed as early as at the age of 4 months. At this age, do
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A marginal structural model by means of additive
2018-11-05
A marginal structural model by means of additive hazard regression was thereafter applied to mortality. Additive hazard regression is a flexible model for survival analyses with the linear dependence of the model facilitating decomposition into direct, indirect, and total effects (Lange & Hansen, 20
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Previous studies conducted in Japan targeted only
2018-11-05
Previous studies conducted in Japan targeted only mothers who cared for children with disabilities and lacked reference subjects, such as mothers of children without disabilities (Toki et al., 2010; Yamaguchi, Takataya & Ogiwara, 2005; Yamaoka et al., 2015; Yatsugi, Suzukamo & Izumi, 2013). Furtherm
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