• Although due to limitations of

  2018-11-05

  

  Although, due to limitations of the current tools and technical challenges, we could not perform direct manipulation of the 11 miRNAs to rescue/inhibit neurogenesis in vivo, we demonstrated that most of these miRNAs are expressed in adult-born hippocampal neurons, and consequently depleted upon the

• The molecular mechanisms underlying calreticulin s effects

  2018-11-05

  

  The molecular mechanisms underlying calreticulin\'s effects on cardiac development continue to be elucidated. It is known that intranuclear translocation of cardiogenic transcription factors is affected by calcineurin, a Ca2+∕calmodulin-regulated cytosolic phosphatase (Crabtree, 1999; Frey et al., 2

• The value of can be significantly lower than

  2018-11-05

  

  The value of can be significantly lower than the initial elastic modulus of the material containing no hydrogen, as The above equation clearly illustrates the strong effect that the concentration of the attached hydrogen particles has on the total elastic modulus: the higher the proportion of the

• Expansion is a canonical white noise expansion in terms

  2018-11-05

  

  Expansion is a canonical white-noise expansion in terms of a wavelet basis, i.e., it is a sum of random quantities multiplied by determinate time-varying functions, in this case, wavelet ones. Amiantov\'s study proved, in particular, the assumption that the probability density functional takes the

• In agreement with the results of

  2018-11-05

  

  In agreement with the results of the previous studies conducted in our laboratory, it was found that the regulation of the STIM2→nSOCE signaling pathway was impaired in 5×FAD mice. It was established that downregulated STIM2 expression was observed as early as at the age of 4 months. At this age, do

• A marginal structural model by means of additive

  2018-11-05

  

  A marginal structural model by means of additive hazard regression was thereafter applied to mortality. Additive hazard regression is a flexible model for survival analyses with the linear dependence of the model facilitating decomposition into direct, indirect, and total effects (Lange & Hansen, 20

• Previous studies conducted in Japan targeted only

  2018-11-05

  

  Previous studies conducted in Japan targeted only mothers who cared for children with disabilities and lacked reference subjects, such as mothers of children without disabilities (Toki et al., 2010; Yamaguchi, Takataya & Ogiwara, 2005; Yamaoka et al., 2015; Yatsugi, Suzukamo & Izumi, 2013). Furtherm

• Only a handful of studies

  2018-11-05

  

  Only a handful of studies examined the RD-health association outside the U.S. and Europe; all revealed strong evidence that, above and beyond absolute income, RD is an important predictor. In research using a large probability sample of Japanese men and women, RD measured by the Yitzhaki Index was f

• Drawing on methods employed from political

  2018-11-05

  

  Drawing on methods employed from political sociology (Clayton & Pontusson, 1998), our study innovatively modeled the state-only family planning and abortion service expenditures both in per capita terms (per woman, age 15–44) and as fraction of total state spending. An additional strength is that ou

• There are several strengths and limitations of this research

  2018-11-05

  

  There are several strengths and limitations of this research that should be noted. Strengths of this research include objective measurement of physical activity and the unique study population. Physical activity was objectively collected using accelerometry, a validated method of assessing time spen

• The type of occupation of

  2018-11-05

  

  The type of occupation of an individual may influence the place of death. We found that Senexin A most of the adult deaths occurred among those with elementary occupations, closely followed by those in agricultural and fishery occupations. However, with the exception of the skilled agricultural/fis

• br Acknowledgements br Introduction It is well

  2018-11-05

  

  Acknowledgements . Introduction It is well established that prenatal events have life-long consequences (Barker, 1992; Cunha & Heckman, 2007; Almond & Currie, 2011). Moreover, events that happen in the postnatal period also different expression for future outcomes and its effects can often be

• Small scale systems or POU systems have become the

  2018-11-05

  

  Small scale systems or POU systems have become the most suitable methods of treatment in the rural areas as it has many advantages. It does not require large volumes of water and is not affected by difficult topography or dispersed settlement. Most small scale systems may not require electricity (So

• A pharmacometabolomics aided pharmacogenomics workflow inclu

  2018-11-05

  

  A “pharmacometabolomics-aided pharmacogenomics” workflow includes sample acquisition and preparation, analysis (NMR or mass spectrometry technologies), data processing and data analysis (targeted and non-targeted) (Mussap et al., 2013). For those familiar with (pharmaco)metabolomics approaches, such

• According to the FDA a prognostic in vitro diagnostic

  2018-11-05

  

  According to the FDA, a prognostic in vitro diagnostic biomarker would need a 510K or de novo approval (class II device), whereas a predictive biomarker would need ldt pre-market approval (PMA, class III device). The main separating factor is that a prognostic biomarker provides you with an estimate

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