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br Conclusions br Acknowledgement br Introduction
2022-08-09
Conclusions Acknowledgement Introduction The macrophage is an important cell species that plays key roles in innate immune responses and inflammatory reactions through phagocytosis of foreign bodies and secretion of inflammatory mediators such as interleukin (IL)-1, tumor necrosis factor (T
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Any brain damage including that caused
2022-08-09
Any BRD4770 damage, including that caused by β-amyloid, triggers activation of microglia, the resident immune cells of the CNS. These cells cluster around amyloid plaques, in which they extend cytoplasmic processes (Combs, 2009). The significance of this response is controversial, but one possibilit
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GPR GPR GPR GPR and
2022-08-09
GPR80, GPR81, GPR82, GPR93 and ψGPR79 all shared identities to P2Y GPCRs or P2Y-like oGPCRs. Previously, at least three different nucleotide receptor phenotypes have been observed in mammalian tissue, including GPCRs activated by smo inhibitor nucleotides (e.g. P2Y1 and P2Y11), uridine nucleotides
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Hair loss in women is polygenic and multifactorial with the
2022-08-09
Hair loss in women is polygenic and multifactorial with the additional influence of environmental factors. Several studies focused on the importance of several genes related to alopecia (Carey et al., 1993, Hillmer et al., 2008, Randall, 2008). FPHL involves progressive hair follicle miniaturization
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Pregnancy per AI results at days post TAI tended
2022-08-09
Pregnancy per AI results at 32 days post TAI tended to differ among GnRH products and was greater for FER and CYS than FAC according to the Tukey-grouping analysis statistical approach (Table 1). In addition, P/AI was greater for cows treated with gonadorelin diacetate products than for cows treated
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The soluble receptor for advanced
2022-08-09
The soluble receptor for advanced glycation end products has been already studied in physiological and pathological pregnancy. In accordance to our previous studies we showed increased sRAGE serum levels in women with threatening premature labor [15] and we described a negative correlation of sRAGE
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To further investigate its role in stresses tolerance OsGly
2022-08-09
To further investigate its role in stresses tolerance, OsGly I was overexpressed in transgenic rice. qRT-PCR and zymologic determination showed that 4-IPP level of OsGly I and the glyoxalase I activity were significantly increased to different extent in the transgenic overexpression lines (Fig. 1,
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Much less is known about the and subunits GlyR subunit
2022-08-09
Much less is known about the α3 and α4 subunits. GlyR α3 subunit immunoreactive synapses are concentrated in discrete bands across the IPL; besides, bipolar, amacrine and ganglion cells have been suggested to express it (Haverkamp et al., 2003, Wässle et al., 2009). In fact, All amacrine express α3β
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ICH induced striatal lesion produced
2022-08-09
ICH-induced striatal lesion produced a reduction of EAAT1 expression analogous to the decreased glutamate uptake at 6 h. The combined reduction of excitatory amino MK-0752 transporters and of glutamate uptake activity might explain the well-known glutamate excitotoxicity following brain ischemia (R
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br Introduction Major depressive disorder MDD is a disease w
2022-08-09
Introduction Major depressive disorder (MDD) is a disease with poorly recognized etiology. Currently used antidepressant drugs, which mainly affect synaptic neurotransmitter levels, show full clinical efficacy in only one third of patients (Rush, 2007). Thus it is now generally accepted that the
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Busulfan br Material and methods br Results br Discussion Fu
2022-08-09
Material and methods Results Discussion Functional characterization of naturally occurring GCK mutations in patients with impaired glucose homeostasis has widened our knowledge of the catalytic and regulatory mechanisms of this enzyme [3]. In this work, we have biochemically characterized a
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Gastric inhibitory polypeptide a hormone
2022-08-09
Gastric inhibitory polypeptide, a hormone belonging to the glucagon-secretin family of peptides, exhibits protection against the neurodegeneration and also stimulates neurogenesis in adult rats in a paracrine manner (Gault and Holscher, 2008, Nyberg et al., 2005, Usdin et al., 1993). The expression
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Prior to proceeding to the main
2022-08-08
Prior to proceeding to the main tests, essential conditions were optimized. At first, we tested whether the parameters that were successful in inducing LacZ gene for the production of β-galactosidase enzymes in E. coli culture system in our previous study would be sufficient to induce LacZ gene in t
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Prior to proceeding to the main
2022-08-08
Prior to proceeding to the main tests, essential conditions were optimized. At first, we tested whether the parameters that were successful in inducing LacZ gene for the production of β-galactosidase enzymes in E. coli culture system in our previous study would be sufficient to induce LacZ gene in t
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The current gold standard for diagnosing BAM or
2022-08-08
The current gold standard for diagnosing BAM or BAD is the measurement of BA turnover rate with radiolabelled tauroselcholic (75selenium) Decanoyl-RVKR-CMK (also known as the SeHCAT retention test). SeHCAT test involves the use of a synthetic analogue of naturally occurring conjugated taurocholic a
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